99 * THE ROCKWOOD FRAILTY INDEX IN TWINSUK
نویسندگان
چکیده
منابع مشابه
Shared genetic influence on frailty and chronic widespread pain: a study from TwinsUK
Introduction frailty is an increased vulnerability to adverse health outcomes, across multiple physiological systems, with both environmental and genetic drivers. The two most commonly used measures are Rockwood's frailty index (FI) and Fried's frailty phenotype (FP). Material and methods the present study included 3626 individuals from the TwinsUK Adult Twin Registry. We used the classical t...
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We previously quantified frailty in aged mice with frailty index (FI) that used specialized equipment to measure health parameters. Here we developed a simplified, noninvasive method to quantify frailty through clinical assessment of C57BL/6J mice (5-28 months) and compared the relationship between FI scores and age in mice and humans. FIs calculated with the original performance-based eight-it...
متن کاملComponents of the Frailty Phenotype in Relation to the Frailty Index: Results From the Toulouse Frailty Platform.
OBJECTIVES The frailty phenotype proposed by Fried and colleagues is a widely used frailty screening instrument, consisting of 5 components: weight loss, exhaustion, low grip strength, slow gait speed, and low physical activity. Although equally considered in the computation of the frailty phenotype score, each of the components may present a specific and different weight in clinical practice. ...
متن کاملChanges with age in the distribution of a frailty index.
Models of human mortality include a factor that summarises intrinsic differences in individual rates of ageing, commonly called frailty. Frailty also describes a clinical syndrome of apparent vulnerability. In a representative, cross-sectional, Canadian survey (n = 66,589) we calculated a frailty index as the mean accumulation of deficits and previously showed it to increase exponentially with ...
متن کاملThe frailty index in Europeans: association with age and mortality.
BACKGROUND the frailty index (FI) is an approach to the operationalisation of frailty based on accumulation of deficits. It has been less studied in Europeans. OBJECTIVE to construct sex-specific FIs from a large sample of Europeans and study their associations with age and mortality. DESIGN longitudinal population-based survey. SETTING the Survey of Health, Ageing and Retirement in Europ...
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ژورنال
عنوان ژورنال: Age and Ageing
سال: 2014
ISSN: 0002-0729,1468-2834
DOI: 10.1093/ageing/afu042.2